WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:chondroitin sulfate metabolic process       ID:GO:0030204
C=54; O=3; E=0.11; R=26.22; rawP=0.0002; adjP=0.0303
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173376 NA NDNF neuron-derived neurotrophic factor 79625 ENSG00000173376
2  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
3  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:biological process       Name:chondroitin sulfate proteoglycan metabolic process       ID:GO:0050654
C=56; O=3; E=0.12; R=25.28; rawP=0.0002; adjP=0.0303
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173376 NA NDNF neuron-derived neurotrophic factor 79625 ENSG00000173376
2  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
3  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:biological process       Name:chondroitin sulfate biosynthetic process       ID:GO:0030206
C=25; O=2; E=0.05; R=37.75; rawP=0.0013; adjP=0.0757
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
2  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:biological process       Name:glycoprotein metabolic process       ID:GO:0009100
C=387; O=5; E=0.82; R=6.10; rawP=0.0012; adjP=0.0757
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169255 NA B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 8706 ENSG00000169255
2  ENSG00000173376 NA NDNF neuron-derived neurotrophic factor 79625 ENSG00000173376
3  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
4  ENSG00000140479 NA PCSK6 proprotein convertase subtilisin/kexin type 6 5046 ENSG00000140479
5  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:biological process       Name:chondroitin sulfate proteoglycan biosynthetic process       ID:GO:0050650
C=27; O=2; E=0.06; R=34.96; rawP=0.0015; adjP=0.0757
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
2  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:biological process       Name:proteoglycan metabolic process       ID:GO:0006029
C=87; O=3; E=0.18; R=16.27; rawP=0.0008; adjP=0.0757
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173376 NA NDNF neuron-derived neurotrophic factor 79625 ENSG00000173376
2  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
3  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:biological process       Name:glycosaminoglycan metabolic process       ID:GO:0030203
C=149; O=3; E=0.32; R=9.50; rawP=0.0038; adjP=0.1240
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173376 NA NDNF neuron-derived neurotrophic factor 79625 ENSG00000173376
2  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
3  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:biological process       Name:proteoglycan biosynthetic process       ID:GO:0030166
C=47; O=2; E=0.10; R=20.08; rawP=0.0044; adjP=0.1240
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
2  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:biological process       Name:aminoglycan metabolic process       ID:GO:0006022
C=158; O=3; E=0.33; R=8.96; rawP=0.0045; adjP=0.1240
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173376 NA NDNF neuron-derived neurotrophic factor 79625 ENSG00000173376
2  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
3  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:biological process       Name:termination of signal transduction       ID:GO:0023021
C=42; O=2; E=0.09; R=22.47; rawP=0.0035; adjP=0.1240
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198873 NA GRK5 G protein-coupled receptor kinase 5 2869 ENSG00000198873
2  ENSG00000100077 NA ADRBK2 adrenergic, beta, receptor kinase 2 157 ENSG00000100077


Database:molecular function       Name:G-protein coupled receptor kinase activity       ID:GO:0004703
C=7; O=2; E=0.02; R=132.33; rawP=9.43e-05; adjP=0.0060
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198873 NA GRK5 G protein-coupled receptor kinase 5 2869 ENSG00000198873
2  ENSG00000100077 NA ADRBK2 adrenergic, beta, receptor kinase 2 157 ENSG00000100077


Database:molecular function       Name:acetylgalactosaminyltransferase activity       ID:GO:0008376
C=33; O=2; E=0.07; R=28.07; rawP=0.0023; adjP=0.0533
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169255 NA B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 8706 ENSG00000169255
2  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:molecular function       Name:catalytic activity       ID:GO:0003824
C=5371; O=20; E=11.60; R=1.72; rawP=0.0025; adjP=0.0533
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135074 NA ADAM19 ADAM metallopeptidase domain 19 8728 ENSG00000135074
2  ENSG00000198873 NA GRK5 G protein-coupled receptor kinase 5 2869 ENSG00000198873
3  ENSG00000114166 NA KAT2B K(lysine) acetyltransferase 2B 8850 ENSG00000114166
4  ENSG00000172331 NA BPGM 2,3-bisphosphoglycerate mutase 669 ENSG00000172331
5  ENSG00000113716 NA HMGXB3 HMG box domain containing 3 22993 ENSG00000113716
6  ENSG00000153982 NA GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 284161 ENSG00000153982
7  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
8  ENSG00000143179 NA UCK2 uridine-cytidine kinase 2 7371 ENSG00000143179
9  ENSG00000141140 NA MYO19 myosin XIX 80179 ENSG00000141140
10  ENSG00000100784 NA RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 9252 ENSG00000100784
11  ENSG00000100077 NA ADRBK2 adrenergic, beta, receptor kinase 2 157 ENSG00000100077
12  ENSG00000172572 NA PDE3A phosphodiesterase 3A, cGMP-inhibited 5139 ENSG00000172572
13  ENSG00000005981 NA ASB4 ankyrin repeat and SOCS box containing 4 51666 ENSG00000005981
14  ENSG00000169255 NA B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 8706 ENSG00000169255
15  ENSG00000178425 NA NT5DC1 5'-nucleotidase domain containing 1 221294 ENSG00000178425
16  ENSG00000135049 NA AGTPBP1 ATP/GTP binding protein 1 23287 ENSG00000135049
17  ENSG00000165983 NA PTER phosphotriesterase related 9317 ENSG00000165983
18  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408
19  ENSG00000116005 NA PCYOX1 prenylcysteine oxidase 1 51449 ENSG00000116005
20  ENSG00000140479 NA PCSK6 proprotein convertase subtilisin/kexin type 6 5046 ENSG00000140479


Database:molecular function       Name:transferase activity       ID:GO:0016740
C=1756; O=9; E=3.79; R=2.37; rawP=0.0101; adjP=0.1616
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169255 NA B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 8706 ENSG00000169255
2  ENSG00000198873 NA GRK5 G protein-coupled receptor kinase 5 2869 ENSG00000198873
3  ENSG00000114166 NA KAT2B K(lysine) acetyltransferase 2B 8850 ENSG00000114166
4  ENSG00000113716 NA HMGXB3 HMG box domain containing 3 22993 ENSG00000113716
5  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
6  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408
7  ENSG00000143179 NA UCK2 uridine-cytidine kinase 2 7371 ENSG00000143179
8  ENSG00000100784 NA RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 9252 ENSG00000100784
9  ENSG00000100077 NA ADRBK2 adrenergic, beta, receptor kinase 2 157 ENSG00000100077


Database:molecular function       Name:kinase binding       ID:GO:0019900
C=399; O=3; E=0.86; R=3.48; rawP=0.0541; adjP=0.2205
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173947 NA C1orf88 chromosome 1 open reading frame 88 128344 ENSG00000173947
2  ENSG00000198873 NA GRK5 G protein-coupled receptor kinase 5 2869 ENSG00000198873
3  ENSG00000114166 NA KAT2B K(lysine) acetyltransferase 2B 8850 ENSG00000114166


Database:molecular function       Name:glycosaminoglycan binding       ID:GO:0005539
C=174; O=2; E=0.38; R=5.32; rawP=0.0540; adjP=0.2205
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173376 NA NDNF neuron-derived neurotrophic factor 79625 ENSG00000173376
2  ENSG00000140479 NA PCSK6 proprotein convertase subtilisin/kexin type 6 5046 ENSG00000140479


Database:molecular function       Name:UDP-glycosyltransferase activity       ID:GO:0008194
C=129; O=2; E=0.28; R=7.18; rawP=0.0315; adjP=0.2205
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169255 NA B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 8706 ENSG00000169255
2  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:molecular function       Name:protein serine/threonine kinase activity       ID:GO:0004674
C=432; O=3; E=0.93; R=3.22; rawP=0.0655; adjP=0.2205
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198873 NA GRK5 G protein-coupled receptor kinase 5 2869 ENSG00000198873
2  ENSG00000100784 NA RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 9252 ENSG00000100784
3  ENSG00000100077 NA ADRBK2 adrenergic, beta, receptor kinase 2 157 ENSG00000100077


Database:molecular function       Name:tubulin binding       ID:GO:0015631
C=161; O=2; E=0.35; R=5.75; rawP=0.0471; adjP=0.2205
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173947 NA C1orf88 chromosome 1 open reading frame 88 128344 ENSG00000173947
2  ENSG00000135049 NA AGTPBP1 ATP/GTP binding protein 1 23287 ENSG00000135049


Database:molecular function       Name:metallopeptidase activity       ID:GO:0008237
C=181; O=2; E=0.39; R=5.12; rawP=0.0580; adjP=0.2205
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135074 NA ADAM19 ADAM metallopeptidase domain 19 8728 ENSG00000135074
2  ENSG00000135049 NA AGTPBP1 ATP/GTP binding protein 1 23287 ENSG00000135049


Database:cellular component       Name:actin cytoskeleton       ID:GO:0015629
C=365; O=3; E=0.68; R=4.38; rawP=0.0305; adjP=0.5400
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077157 NA PPP1R12B protein phosphatase 1, regulatory subunit 12B 4660 ENSG00000077157
2  ENSG00000114166 NA KAT2B K(lysine) acetyltransferase 2B 8850 ENSG00000114166
3  ENSG00000141140 NA MYO19 myosin XIX 80179 ENSG00000141140


Database:cellular component       Name:trans-Golgi network       ID:GO:0005802
C=128; O=2; E=0.24; R=8.33; rawP=0.0239; adjP=0.5400
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000173947 NA C1orf88 chromosome 1 open reading frame 88 128344 ENSG00000173947
2  ENSG00000078328 NA RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 54715 ENSG00000078328


Database:cellular component       Name:Golgi apparatus part       ID:GO:0044431
C=672; O=4; E=1.26; R=3.17; rawP=0.0358; adjP=0.5400
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169255 NA B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 8706 ENSG00000169255
2  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
3  ENSG00000140479 NA PCSK6 proprotein convertase subtilisin/kexin type 6 5046 ENSG00000140479
4  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:cellular component       Name:extracellular matrix       ID:GO:0031012
C=426; O=3; E=0.80; R=3.75; rawP=0.0450; adjP=0.5400
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000074527 NA NTN4 netrin 4 59277 ENSG00000074527
2  ENSG00000173376 NA NDNF neuron-derived neurotrophic factor 79625 ENSG00000173376
3  ENSG00000140479 NA PCSK6 proprotein convertase subtilisin/kexin type 6 5046 ENSG00000140479


Database:cellular component       Name:Golgi membrane       ID:GO:0000139
C=553; O=3; E=1.04; R=2.89; rawP=0.0841; adjP=0.5874
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169255 NA B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 8706 ENSG00000169255
2  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
3  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:cellular component       Name:membrane       ID:GO:0016020
C=7811; O=19; E=14.66; R=1.30; rawP=0.0864; adjP=0.5874
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000261115 NA TMEM178B transmembrane protein 178B 100507421 ENSG00000261115
2  ENSG00000135074 NA ADAM19 ADAM metallopeptidase domain 19 8728 ENSG00000135074
3  ENSG00000198873 NA GRK5 G protein-coupled receptor kinase 5 2869 ENSG00000198873
4  ENSG00000106714 NA CNTNAP3 contactin associated protein-like 3 79937 ENSG00000106714
5  ENSG00000039537 NA C6 complement component 6 729 ENSG00000039537
6  ENSG00000153982 NA GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 284161 ENSG00000153982
7  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
8  ENSG00000141140 NA MYO19 myosin XIX 80179 ENSG00000141140
9  ENSG00000168216 NA LMBRD1 LMBR1 domain containing 1 55788 ENSG00000168216
10  ENSG00000172572 NA PDE3A phosphodiesterase 3A, cGMP-inhibited 5139 ENSG00000172572
11  ENSG00000169255 NA B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 8706 ENSG00000169255
12  ENSG00000116005 NA PCYOX1 prenylcysteine oxidase 1 51449 ENSG00000116005
13  ENSG00000113583 NA C5orf15 chromosome 5 open reading frame 15 56951 ENSG00000113583
14  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408
15  ENSG00000077157 NA PPP1R12B protein phosphatase 1, regulatory subunit 12B 4660 ENSG00000077157
16  ENSG00000074527 NA NTN4 netrin 4 59277 ENSG00000074527
17  ENSG00000154529 NA CNTNAP3B contactin associated protein-like 3B 728577 ENSG00000154529
18  ENSG00000168675 NA C18orf1 chromosome 18 open reading frame 1 753 ENSG00000168675
19  ENSG00000140479 NA PCSK6 proprotein convertase subtilisin/kexin type 6 5046 ENSG00000140479


Database:cellular component       Name:extracellular region       ID:GO:0005576
C=2140; O=7; E=4.02; R=1.74; rawP=0.0979; adjP=0.5874
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000074527 NA NTN4 netrin 4 59277 ENSG00000074527
2  ENSG00000106714 NA CNTNAP3 contactin associated protein-like 3 79937 ENSG00000106714
3  ENSG00000173376 NA NDNF neuron-derived neurotrophic factor 79625 ENSG00000173376
4  ENSG00000039537 NA C6 complement component 6 729 ENSG00000039537
5  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
6  ENSG00000140479 NA PCSK6 proprotein convertase subtilisin/kexin type 6 5046 ENSG00000140479
7  ENSG00000116005 NA PCYOX1 prenylcysteine oxidase 1 51449 ENSG00000116005


Database:cellular component       Name:Golgi apparatus       ID:GO:0005794
C=1180; O=5; E=2.21; R=2.26; rawP=0.0668; adjP=0.5874
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169255 NA B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 8706 ENSG00000169255
2  ENSG00000173947 NA C1orf88 chromosome 1 open reading frame 88 128344 ENSG00000173947
3  ENSG00000154080 NA CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 83539 ENSG00000154080
4  ENSG00000140479 NA PCSK6 proprotein convertase subtilisin/kexin type 6 5046 ENSG00000140479
5  ENSG00000147408 NA CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 55790 ENSG00000147408


Database:cellular component       Name:lytic vacuole       ID:GO:0000323
C=345; O=2; E=0.65; R=3.09; rawP=0.1364; adjP=0.6463
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000168216 NA LMBRD1 LMBR1 domain containing 1 55788 ENSG00000168216
2  ENSG00000116005 NA PCYOX1 prenylcysteine oxidase 1 51449 ENSG00000116005


Database:cellular component       Name:lysosome       ID:GO:0005764
C=345; O=2; E=0.65; R=3.09; rawP=0.1364; adjP=0.6463
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000168216 NA LMBRD1 LMBR1 domain containing 1 55788 ENSG00000168216
2  ENSG00000116005 NA PCYOX1 prenylcysteine oxidase 1 51449 ENSG00000116005




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).